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Severe but Not Moderate Vitamin B12 Deficiency impairs lipid profile, induces adiposity, and leads to adverse gestational outcome in female C57BL/6 mice

To obtain the specific labeling patterns, intracellular metabolites were extracted and analyzed using GC/MS to determine multiple ion detections (MIDs) (corrected for natural isotope abundance), which reflect relative metabolic fluxes 28

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They may provide nutritional support during a caloric deficit, and they also help the compounding pharmacy demonstrate that the formulation is "personalized" rather than a direct copy of the brand-name product